The laboratory is engaged in the development and optimisation of molecular methods for the study of modern DNA. It offers the opportunity to work with a high copy number of molecular products and to test new procedures before they are applied to bio-archaeological material. The most important method used in this laboratory is “targeted enrichment”, that is the enrichment of the target sequences for the isolation of human or microbial DNA from complex samples. If the endogenous DNA content is low, this molecular method offers a number of procedural approaches which allow scientists to focus their studies for example on population genetics, on markers of genetic disease, and on the reconstruction of the complete genome of pathogens. To avoid cross-contamination, the modern DNA laboratory is physically separate from the ancient DNA laboratory.
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